Fluoride treatment in corticosteroid induced osteoporosis.

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Fluoride treatment in corticosteroid induced osteoporosis.

Severe osteoporosis with multiple vertebral fractures occurred in two girls receiving prolonged high dose corticosteroids for relapsing dermatomyositis. Sodium fluoride, supplemented with calcium and vitamin D, helped control secondary osteoporosis in one case and should be considered as part of the curative treatment of corticoid induced osteoporosis.

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Is addition of sodium fluoride to cyclical etidronate beneficial in the treatment of corticosteroid induced osteoporosis?

OBJECTIVE To investigate whether administration of sodium fluoride (NaF) in addition to cyclical etidronate has a positive effect on bone mineral density (BMD) in patients with established osteoporosis during continued treatment with corticosteroids. PATIENTS AND METHODS 47 patients who were receiving treatment with corticosteroids were included in a two year randomised, double blind, placebo...

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Prevention and Treatment of Corticosteroid-Induced Osteoporosis

Osteoporosis is one of the most serious complications of corticosteroid treatment. Loss of bone mineral density (BMD) and fractures occur early in the course of corticosteroid treatment, and thus early recognition of fracture risk and effective intervention based on evidence-based-medicine (EBM) are needed. A study of meta-analysis representing the highest level in a hierarchy of evidence showe...

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Fluoride treatment in osteoporosis.

The use of fluoride for the treatment of established vertebral osteoporosis in adults with the symptomatic crush fracture syndrome is approved for use in 8 European countries.' This treatment was suggested by the low prevalence of osteoporosis in some areas where the drinking water contained moderately high concentrations of fluoride` and by the enormously increased bone density characteristic ...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1986

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.61.12.1230